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The Effect of Apricot Kernels Extract

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Apricot kernels extract for Rosaceae peach Prunus persica (L.) Batsch seed, almond P.amygdalus Batsch seed, apricot P. armeniaca L. seeds, Li P.Salicina Lindl. seeds, plum P.mume (Sieb et Zucc. seed kernels, English hawthorn Crataegus oxyacantha Linn, Tianshan pepper Sorbus tianschanica Rupr. bark, Loquat Eriobotrya japonica (Thunb) Lindl. seeds with lower gas cough and asthma, laxative effect.

Function of the attending:
First, cough and asthma role the bitter almond contains laetrile, laetrile enzyme. Apricot kernels extract can be gut microbes in the body itself contains bitter almond enzyme hydrolysis, produce trace amounts of hydrocyanic acid and benzaldehyde, has inhibitory effect on respiratory center, to cough, and asthma. Using guinea pig organs in vitro test, almond extract can reduce organ of ammonia water stimulation sensitivity, fight histamine, acetylcholine and barium chloride excitation of airway smooth muscle, has obvious cough. SO2 to cough method proves that the mice gastric laetrile 1 mg/kg, 10 mg/kg and 100 mg/kg after 30 min, the frequency of cough inhibition rate of 26%, 22.8% and 25.3% respectively.

Second, the effects on the digestive system Almond taste bitter under gas and fatty oil. Fatty oil can improve the lubrication of the intestinal contents of mucosa, so the almond runchang purge function. Laetrile in the decomposition of enzyme action form hydrocyanic acid at the same time, also produce benzene, formaldehyde, which can inhibit the activity of pepsin, thereby affect the digestive function. Almond water-soluble part of pepsin hydrolyzate to the dose of 500 mg/kg of carbon tetrachloride treatment rats to medicine, found that it can suppression of AST, ALT and hydroxyproline content increases, and inhibit the euglobulin dissolution time. Water soluble part of the pepsin hydrolyzate almond can inhibit rat liver connective tissue hyperplasia, but can't restrain rats caused by D - galactose amine AST and ALT levels.

Third, anti-inflammation and analgesic action Skim the water extract of bitter almond of caused by acetic acid in mice body torsion reaction and formation of granulomatous inflammation in rats caused by cotton ball has inhibitory effect. With rats' foot joint swelling method, 40 mg/kg intravenous almond water-soluble protein components of KR - A, KR - B5mg/kg inhibit inflammation. Their feet swollen carageen glue in rats, through the mouth eat ED50 were 13.9 mg/kg and 6.4 mg/kg. Mouse hot plate method and acetic acid twisting method confirmed that laetrile has analgesic effect, but different from Brown analgesics. Laetrile decomposition of static benzoin condensation of benzaldehyde generates benzoin enzyme action. Analgesic effects of benzoin, therefore the domestic treatment of advanced liver cancer with bitter apricot kernel can relieve the pain of patients, some even without taking painkillers.

Forth, antitumor effect In the early 20th century, laetrile separated from almond, for the first time in 1920 in the United States for the first time laetrile used in the treatment of tumor. Ernest Krebs, Ph.D., is the first in the United States will laetrile used in medicine, and it is called a vitamin B17. Laetrile since the 1950 s, though in the United States, Mexico and other countries widely used to treat tumor, commodity called vitamin B17 or laetrile, but about the antitumor function of the laetrile have not been admitted that the FDA has been controversial in academia, there are two opposite views. In favor of one party thinks that is a kind of vitamin B17 laetrile, have the function of the prevention and treatment of tumor, and puts forward some theory and experimental data. The opposite viewpoint thinks, laetrile not vitamin, also does not have anti-cancer effect, or even toxic substances. About the antitumor function of the laetrile is still in dispute, but in Belgium, Germany, Italy, Mexico and the Philippines, more than 20 countries, manufacture and use laetrile is legal.

Fifth, fall blood sugar function Laetrile has antitumor drug control for the role of diabetes caused by alloxan. Hyperglycemia in mice induced by alloxan method has been proved that celiac injection of 3 g/kg laetrile in advance after 48 h blood glucose measurement, the results show that laetrile can specifically inhibit alloxan caused by elevated blood sugar, strength and laetrile concentrations in the blood.

Apricot kernels extract oil and insecticide, antiseptic effect, in vitro test of ascaris lumbricoides, earthworms have killing effect, and typhoid and paratyphoid coli has antibacterial action. Almonds have pinworm and trichomonas infection, treatment of aplastic anemia. Laetrile in the treatment of rabbit schistosomiasis liver fibrosis and liver fibrosis in rats caused by carbon tetrachloride also showed obvious curative effect.
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